Human abdominal aortic aneurysm RNA-Seq Dataset

To analyze transcriptomic differences between human healthy aortas and abdominal aortic aneurysms, identifying differentially expressed genes and related pathways. Abdominal aortic aneurysm pathogenesis remains poorly understood. RNA-Seq provides a comprehensive approach to uncover inflammation- and immune-related mechanisms, offering potential diagnostic and therapeutic targets. A total of 4,327 DEGs were identified, with 2,473 upregulated and 1,854 downregulated genes. Upregulated genes were strongly associated with neutrophil activation, inflammatory response, and iron metabolism, including key genes such as S100A8, IL6, and