S1 Dataset -

(Sheet A) NCBI accession numbers. (Sheet B) Amino acid variability of Env-J sequences obtained from databases and type of selection pressure applied to individual amino acids calculated based on the ratio of non-synonymous to synonymous substitutions (dN/dS). The positions of amino acids substituted in our experiments are highlighted in gray, the start of the TM is indicated by a double line. (XLSX)