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Additional file 9 of Age-associated changes in the circulating human antibody repertoire are upregulated in autoimmunity

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Figshare2020-10-06 更新2026-04-28 收录
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Additional file 9: Table S1. The complete dataset for the Training Cohort (Experiment 1068). Dataset consists of meta data, raw foreground intensity data, and transformed data on which most analyses were performed. Meta data (META) uses row name ‘scan id’ as unique identifier that can be matched with other data files. Meta data columns include peptide array reagent, batch, assay, infection, and demographic information for a given sample. The foreground (FG) intensity values are formatted with rows as peptide probes and columns as donors. Each value is in range of [0,65,535]. The first column has row names, which is probe name, underscore, peptide sequence, where probe name is created based on the “X” and “Y” physical locations of where the probe is found on the array. The first row has column name ‘scan id’, which can be matched to the META rownames. The transformed data (LFG) is log-transformed data with shrinkage: log10(x + 100). This transform helps data follow a more homoskedastic distribution and decreases the influence of low intensity probes.
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2020-10-06
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