Additional file 8: Table S1. Table S1 complements the Material and Methods part listing IC50 values of single compounds (data presented in Additional file 2: Fig. S2), compound concentrations, calcula
The trapping of Poly-ADP-ribose polymerase (PARP) on DNA caused by PARP inhibitors (PARPi) triggers acute DNA replication stress and synthetic lethality (SL) in BRCA2-deficient cells. Hence, DNA
Amplification and expression of the MYC oncogene in tumor cells, including ovarian cancer cells correlates with poor responses to chemotherapy. As MYC is not directly targetable, we have analyzed mole
