Stereoselective Synthesis of Morpholines via Copper-Promoted Oxyamination of Alkenes
收藏NIAID Data Ecosystem2026-03-09 收录
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A new copper(II) 2-ethylhexanoate-promoted addition of an alcohol and an amine across an alkene (oxyamination) is reported. The alcohol addition is intramolecular, while coupling with the amine occurs intermolecularly. Several 2-aminomethyl morpholines were synthesized in good to excellent yields and diastereoselectivities.
创建时间：
2016-02-20
