Activation of the P-TEFb Complex by Lethal Prostate Cancer-Associated Enhancer RNAs

ChEBI2016-02-12 更新2026-07-12 收录

前列腺癌分子机制

增强子RNA功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-55032 数据链接链接失效反馈

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资源简介：

Activation of the P-TEFb Complex by Lethal Prostate Cancer-Associated Enhancer RNAs

创建时间：

2016-02-12

TFEB promotes prostate cancer progression via regulating ABCA2-dependent lysosomal biogenesis

前列腺癌分子机制

基因表达调控

The goals of this study is to find effect of overexpression-TFEB in prostate cancer cell (DU145 cell line). Overall design: To further explore the potential molecular mechanisms of how TFEN affects ca

NIAID Data Ecosystem80

Examining alterations in gene expression of PC3-wt (PSMA -ve) vs PC3-PSMA (PSMA +ve) cells

前列腺癌分子机制

基因表达谱分析

The biological role of PSMA, a biomarker expressed in prostate cancer and by the neovasculature of solid tumors, remains unknown. Although PSMA processes folates in our duodenum, and in the brain clea

NIAID Data Ecosystem50

Zinc Finger 280B Regulates sGCα1 and p53 in Prostate Cancer Cells

前列腺癌分子机制

肿瘤蛋白调控

The Zinc Finger (ZNF) 280B protein was identified as an unexpected target of an shRNA designed for sGCα1. Further analysis showed that these two proteins are connected in another way, with 280B up-reg

Figshare2016-01-18 更新10

Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells

前列腺癌分子机制

激素受体功能

Androgen receptor (AR) signaling pathway remains the foremost target of novel therapeutics for castration-resistant prostate cancer (CRPC). However, the expression of constitutively active AR variants

NIAID Data Ecosystem60

identifying all AR binding regions in PC346C cell line. identifying all AR binding regions in PC346C cell line

前列腺癌分子机制

转录因子结合位点鉴定

The Androgen Receptor plays in general an important role in Prostate Cancer biology. The Androgen Receptor orchestrates as transcription factor the activity of AR-regulated genes at destinct genomic r

NIAID Data Ecosystem40

Activation of the P-TEFb Complex by Lethal Prostate Cancer-Associated Enhancer RNAs

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