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Leishmania transcriptome under heme limitation reveals LHR2, a protein required for leishmaniasis development

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP577414
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Leishmania parasites cause leishmaniasis, a neglected disease without adequate treatments. Its heme-auxotrophy is one of its Achilles heel. A transcriptomic study of heme-regulated genes identifies LHR2, an essential gene for Leishmania intracellular replication and development of pathology proposed as a novel drug target.
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2026-02-11
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