Crystal Structure of human tryptase with potent non-peptide inhibitor
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Crystal Structure of human tryptase with potent non-peptide inhibitor Descriptor: (5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone, Tryptase beta 2 Authors: Spurlino, J.C, Barnakov, S.A, Lewandowski, F, Milligan, C. Deposit date: 2007-10-02 Release date: 2008-02-26 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives Bioorg.Med.Chem.Lett., 18, 2008
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2007-10-02
