Here we present and validate a non-invasive chromosome screening method based on sequencing the genomic DNA secreted into the culture medium from the human blastocyst. By using multiple annealing and
In order to investigate the influence of the molecular karyotype based on single nucleotide polymorphism (SNP) microarray on embryonic development potential in preimplantation genetic diagnosis (PGD),
Background: Preimplantation genetic test for monogenic disorders (PGT-M) has been used to select genetic disease-free embryos for implantation during in vitro fertilization (IVF) treatment. However, e