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Direct reprogramming of hepatic myofibroblasts into hepatocytes in vivo attenuates liver fibrosis

ChEBI2016-02-22 更新2026-07-12 收录

纤维化治疗

细胞重编程

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-76843 数据链接链接失效反馈

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资源简介：

Direct reprogramming of hepatic myofibroblasts into hepatocytes in vivo attenuates liver fibrosis

应用场景：

创建时间：

2016-02-22

纤维化治疗

CFTR药物研究

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding for a chloride ion channel. Membrane expression of CFTR is negatively regul

NIAID Data Ecosystem70

Direct reprogramming of mouse fibroblasts into functional skeletal muscle progenitors. Mus musculus

细胞重编程

骨骼肌细胞

Skeletal muscle harbors quiescent stem cells termed satellite cells and proliferative progenitors termed myoblasts, which play pivotal roles during muscle regeneration. However, current technology doe

NIAID Data Ecosystem50

Direct conversion from human dermal fibroblasts into urothelial cells by defined factors. Homo sapiens

细胞重编程

尿路上皮细胞

In this project, we converted human dermal fibroblasts into urothelial cells by introducing four retroviral vectors. Directly converted urothelial cells were sequenced in a purified state (n = 3). Neg

NIAID Data Ecosystem30

Bulk RNA sequencing of chemical-induced intermediate cells

细胞重编程

RNA测序分析

This study aims to investigate the individual effect of cocktail VCRTc on the direct reprogramming process.We collected cells as follows: mouse chondrocytes (mchons), mouse embryonic fibroblasts(MEFs)

NIAID Data Ecosystem70

Additional file 5 of Unraveling the 2,3-diketo-l-gulonic acid-dependent and -independent impacts of l-ascorbic acid on somatic cell reprogramming

细胞重编程

维生素C生化作用

Additional file 5: Table S4. Reagents and resources used in the current studies.

NIAID Data Ecosystem40