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Crystal structure of the non-neutralizing and ADCC-potent C11-like antibody N12-i3 in complex with HIV-1 clade A/E gp120, the CD4 mimetic M48U1, and the antibody N5-i5.

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Protein Data Bank Japan2023-11-15 更新2026-03-21 收录
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Crystal structure of the non-neutralizing and ADCC-potent C11-like antibody N12-i3 in complex with HIV-1 clade A/E gp120, the CD4 mimetic M48U1, and the antibody N5-i5. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody N12-i3 Fab heavy chain, Antibody N12-i3 light chain, ... Authors: Tolbert, W.D, Gohain, N, Pazgier, M. Deposit date: 2017-06-12 Release date: 2017-11-15 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region. Structure, 25, 2017
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2017-06-12
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