Antimicrobial susceptibilities and chloramphenicol accumulation in E. aerogenes strains.
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aRatio of chloramphenicol accumulated at 600 s with and without CCCP.bE. aerogenes control strains used: ATCC 15038 reference strain that expresses a normal level of the AcrAB efflux system; EAEP294 (acrA− deleted mutant)and EAEP289 that exhibits overexpression of the AcrAB efflux system.cN.D: not determined.Antimicrobial agent abbreviations: IMI, Imipenem; CEF, Cefepime; TET, Tetracycline; CHL, Chloramphenicol; NAL, Nalidixic Acid; NFL, Norfloxacin; OFL, Ofloxacin; SPA, Sparfloxacin; CIP, Ciprofloxacin. Values in parentheses were determined in the presence of efflux pump inhibitor PAßN at 26.3 µg/ml.
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2015-12-02
