Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor
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Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor Descriptor: 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide, L(+)-TARTARIC ACID, Serine/threonine-protein kinase PLK1, ... Authors: Bossi, R.T, Bertrand, J.A. Deposit date: 2009-10-20 Release date: 2010-05-19 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors J.Med.Chem., 53, 2010
创建时间：
2009-10-20
