S1 Data - Development and characterization of a reverse genetics system for the lineage II Chicava strain of Machupo virus in a guinea pig model
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Fig 1a Raw Data. Multiplication kinetics of rescued MACV Chicava compared to the wild-type isolate in Vero cells at a MOI of 0.01. Values represent PFU/mL. Fig 2a Raw Data. Survival of guinea pigs (n = 5 per group) challenged with 104 pfu of the indicated MACV strains. A = alive, EU = euthanized. Percentages indicate survival rate of animals in each group at each dpi. Fig 2b Raw Data. Body weight loss by percentage as compared to baseline (0 dpi). Fig 2c Raw Data. Body temperature readings of infected guinea pigs. A red asterisk (*) indicates a broken transponder chip that prevented collection of further body temperature readings. (XLSX)
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2025-01-24



