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Effect of Age on Severity and Recovery of Acute Multiple Sclerosis Attack

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE146383
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Pediatric MS patients suffer from severe first and second relapse but better recovery explained by difference in age-restricted transcriptional profiles associated with antigen-presentation and B-cell activation Herein, we compared the blood mononuclear cell transcriptome of pediatric and adult MS patients with recovery (PDMS-rec, ADMS-rec) and without recovery (PDMS-norec, ADMS-norec) 6 months after relapse. Healthy pediatric and adult subjects (PDC, ADC) were used as controls. A total of 30 MS patients (14 PDMS-rec and ADMS-rec, 16 PDMS-norec and ADMS-norec , 55 PDC andADC) that met the inclusion criteria were analyzed.
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2021-01-27
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