HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 29
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HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 29 Descriptor: 5-{(3R)-3-methyl-4-[(1R,2R)-2-methylcyclopropane-1-carbonyl]piperazin-1-yl}-3-(1-methyl-1H-pyrazol-4-yl)pyrazine-2-carbonitrile, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Authors: Lesburg, C.A, Augustin, M.A. Deposit date: 2019-03-25 Release date: 2019-12-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Discovery and optimization of heteroaryl piperazines as potent and selective PI3K delta inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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2019-03-25
