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α‑Ketophosphonates as Ester Surrogates: Isothiourea-Catalyzed Asymmetric Diester and Lactone Synthesis

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Figshare2016-02-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Ketophosphonates_as_Ester_Surrogates_Isothiourea_Catalyzed_Asymmetric_Diester_and_Lactone_Synthesis/2301460
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Isothiourea HBTM-2.1 catalyzes the asymmetric Michael addition/lactonization of aryl- and alkenylacetic acids using α-keto-β,γ-unsaturated phosphonates as α,β-unsaturated ester surrogates, giving access to a diverse range of stereodefined lactones or enantioenriched functionalized diesters upon ring-opening.
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2016-02-17
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