MerlinS13 phosphorylation controls meningioma Wnt signaling and magnetic resonance imaging features
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1102120
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To investigate the effect of Merlin rescue on cell proliferation in 3D, we grew subcutaneous xenografts from NF2-deficient CH-157MN meningioma cells harboring doxycycline inducible WT-Merlin. Mice were treated with or without doxycycline and Merlin induction was confirmed 24 hours after induction with Western blot. We performed bulk RNA sequencing on three Merlin-deficient tumors and four Merlin rescue tumors.
创建时间：
2024-04-19
