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收藏资源简介:
This repository contains: LMM selection summary statistics, including versions restricted to HapMap3 SNPs (we also provide deflated GLMM selection Z-scores, used for locus discovery). Per-chromosome fine-mapping results using LMM selection statistics (including 95% credible sets), performed as described in the methods. GWAS summary statistics analyzed in this study, other than the ones generated by the FinnGen consortium, which can be accessed at https://www.finngen.fi/en/access_results. gsMap results for LMM selection statistics analyzed with the human-gut single-cell, spatial transcriptomics dataset by (Hickey et al. 2023, Nature), as described in the methods. We provide: Raw gsMap output for each sample, when annotating cells by 1 of 4 increasingly fine-grained annotations. Annotation-level enrichment p-values across all intestinal regions, or across all samples for a given intestinal region, obtained by the gsMap Cauchy aggregation test. We provide plots for annotation-level p-values (subfolder per-annotation_enrichment_pval_plots)



