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The crystal structure of PI3Kdelta with compound 34

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Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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The crystal structure of PI3Kdelta with compound 34 Descriptor: 2,4-diamino-6-{[(1S)-1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl]amino}pyrimidine-5-carbonitrile, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Authors: Somoza, J.R, Villasenor, A.G. Deposit date: 2016-02-12 Release date: 2017-02-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.372 Å) Cite: The Design and Synthesis of Potent, Selective and Metabolically Stable PI3K[delta] Inhibitors To be published

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2016-02-12
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