Chromosomes and plasmids are two forms of genetic carriers. Exogenous yeast artificial chromosomes are also considered as yeast centromeric plasmids in many cases. Here, we used state-of-the-art seque

NIAID Data Ecosystem50

Establishment of 3D chromatin structure after fertilization and the metabolic switch at the morula-to-blastocyst transition require CTCF [Hi-C]

染色质结构

胚胎发育

The eukaryotic genome is tightly packed inside the nucleus, where it is organized in 3D at different scales. This structure is driven and maintained by different chromatin states and by architectural

NIAID Data Ecosystem30

ncPRC1RYBP bound to H2AK119Ub/H1.4 chromatosome

染色质结构

表观遗传调控

ncPRC1RYBP bound to H2AK119Ub/H1.4 chromatosome Descriptor: DNA (187-MER), E3 ubiquitin-protein ligase RING2, Histone H1.4, ... Authors: Godinez-Lopez, V, Valencia-Sanchez, M.I, Armache, J.P, Armache,

Protein Data Bank Japan2025-01-15 更新60

Chromatin architecture is indirectly regulated by CDK7 transcriptional activity. Chromatin architecture is indirectly regulated by CDK7 transcriptional activity

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CDK7

Cyclin Dependent Kinase 7 (CDK7) is the core catalytic subunit of Cyclin Activating Kinase (CAK), a complex that has dual roles in cell cycle progression and transcription. While several CDK7 inhibito

NIAID Data Ecosystem40

Nucleosome positioning in the IMR90 cell line. Homo sapiens

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