Demographics and concentration of metabolites.

Demographical and clinical values of FRDA patients before (FRDA baseline) and after stimulation (FRDA rhuEPO) with rhuEPO shown as comparison to healthy control subjects (Controls). Absolute concentrations of metabolites (PCr, Pi) in resting state, at exercise abruption and at the end of regeneration are given as mmol/l by using ATP as an internal standard. Intracellular pH was calculated from the chemical shift of Pi. Values are given as mean and standard deviation (SD). Abbreviations: SARA (scale for the assessment and rating of ataxia), Repeats (GAA repeat of the shorter allele is given), Duration (disease duration), PCr (phosphocreatine), Pi (inorganic phosphate), FRDA (Friedreich ataxia), rhuEPO (recombinant human erythropoietin).