Brca2 homozygous mutant prostates (Brca2F/F;PBCre4) have hyperplasia (Hyp) at 10–14 months and LG PIN at 15–20 months. Brca2 homozygous Trp53 heterozygous mutant prostates (Brca2F/F;Trp53F/+;PBCre4) h
Prostate cancer research has been predominantly focused on adult exposures and risk factors. However, because the prostate develops during gestation and early life, exposure to external factors, such
To evaluate the premalignant potential of high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical small acinar proliferation (ASAP). Patients diagnosed with monofocal HGPIN (mHGPIN), wides
