Treatment-Resistant Depression Synthetic Dataset v1.0

Research-Grade Synthetic Dataset for Treatment-Resistant Depression (TRD) This dataset contains 9,997 synthetic longitudinal records representing 1,000 patients with Treatment-Resistant Depression (ICD-10: F33.2), defined as Major Depressive Disorder failing ≥2 adequate antidepressant trials. Key Features: 32 clinical variables including HAM-D, PHQ-9, QIDS-SR16, MADRS scores Treatment trajectories: esketamine, TMS, ECT, MAOIs, augmentation strategies 8-12 visits per patient over 12-18 months Privacy-preserving: k-anonymity ≥12, differential privacy ε<1.0 Generated by MentalData.io using clinically-validated distributions. No real patient data. License: CC BY-NC 4.0