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PKA and PLC pathways sensitize TRPA1 to NO donor.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_PKA_and_PLC_pathways_sensitize_TRPA1_to_NO_donor_/548474
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Summary of the percent of responsive “sensitized” DRG neurons to SNAP (3 mM), capsaicin (10 µM), and mustard oil (0.5 mM) from mice of the indicated genotypes (V1 represents TRPV1 and A1 represents TRPA1). DRG neurons were incubated with forskolin (100 µM) and m-3M3FBS (50 µM) for 10 min prior to SNAP application.*ATP (100 µM) was applied in the last of the experiment as a positive control. Approximately 20% of total DRG neurons were activated by application of ATP.
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2015-12-02
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