Cryo-EM structure of the human CAK bound to ICEC0942 (PHENIX-OPLS3e)
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Cryo-EM structure of the human CAK bound to ICEC0942 (PHENIX-OPLS3e) Descriptor: (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, CDK-activating kinase assembly factor MAT1, Cyclin-H, ... Authors: Greber, B.J, Remis, J, Ali, S, Nogales, E. Deposit date: 2020-12-05 Release date: 2021-02-10 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: 2.5 angstrom -resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942. Biophys.J., 120, 2021
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2020-12-05
