ELONA results of the ssDNA aptamer CSIR 2.11 tested as a detection reagent for active TB in sputum samples.

1The two donors who gave a single sample were not detected as TB positive in the ELONA. Of the 13 donors that gave two sputum samples, two cases had both samples as positive and in three of the cases only the second sample gave a positive reading.*Youden’s index is one that selects the best trade-off between sensitivity and specificity using a ROC curve, and may not correspond to a cut-point that rules in or rules out disease.