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Epigenetic determinants of self-renewal in glioblastoma [ATAC-seq]

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=72f7b8559deefec0abd337e849ddfd5f
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We over-expressed an epigenetic regulator in a glioblastoma (GBM) primary culture from an adult patient. These GBM cells have cancer stem cell phenotypes, as they have self-renewal properties and tumor initiation potential when transplanted in immunocompromised mice. ATAC-seq was performed on cells over-expressing the epigenetic regulator and control cells expressing EGFP.
提供机构:
University Health Network
创建时间:
2022-02-20
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