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Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate Descriptor: 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... Authors: Ashton, K.S, Andrews, K.L, Bryan, M.C, Chen, J, Chen, K, Chen, M, Chmait, S, Croghan, M, Cupples, R, Fotsch, C, Helmering, J, Jordan, S.R, Kurzeja, R.J, Michelsen, K, Pennington, L.D, Poon, S.F, Sivits, G, Van, G, Vonderfecht, S.L, Wahl, R.C, Zhang, J, Lloyd, D.J, Hale, C, St Jean, D.J. Deposit date: 2013-09-18 Release date: 2014-03-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept. J.Med.Chem., 57, 2014
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2013-09-18
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