Epigenomic Regulation of Human T-Cell Leukemia Virus by Chromatin-Insulator CTCF. Epigenomic Regulation of Human T-Cell Leukemia Virus by Chromatin-Insulator CTCF
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA722402
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资源简介：
We compared histone modifications of wild type and HTLV-1ΔCTCF provirus by ChIP sequencing and observed that loss of the vrial CTCF binding site in HTLV-1 results in increased histone methylation 5’ and 3’ of the CTCF site, suggesting that CTCF binding may act as a boundary element to epigenetic modification. Overall design: Examine H3K4me3, H3K36me3 and H3K27me3 marks associated with the wild type and mutant HTLV-1 provirus in PBMCs and JET cells
创建时间：
2021-04-16
