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Synthesis of <i>tert</i>-Butyl 6-Oxo-2-azaspiro[3.3]heptane-2-carboxylate

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NIAID Data Ecosystem2026-03-06 收录
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Two efficient and scaleable synthetic routes to previously unknown bifunctional tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate are described. This compound and related intermediates described herein are useful for further selective derivation on the azetidine and cyclobutane rings providing a convenient entry point to novel compounds accessing chemical space complementary to piperidine ring systems.

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2009-08-20
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