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Crystal structure of CYP3A4 ligated to oxazole-substituted desoxyritonavir

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of CYP3A4 ligated to oxazole-substituted desoxyritonavir Descriptor: Cytochrome P450 3A4, N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-N-[(2R,5R)-5-{[(1,3-oxazol-5-ylmethoxy)carbonyl]amino}-1,6-diphenylhexan-2-yl]-L-valinamide, PROTOPORPHYRIN IX CONTAINING FE Authors: Sevrioukova, I.F, Poulos, T.L. Deposit date: 2012-11-27 Release date: 2013-04-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.718 Å) Cite: Pyridine-Substituted Desoxyritonavir Is a More Potent Inhibitor of Cytochrome P450 3A4 than Ritonavir. J.Med.Chem., 56, 2013
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2012-11-27
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