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Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response

NIAID Data Ecosystem2026-05-02 收录

基因编辑治疗

造血干细胞功能

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE119597 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-07-10

基因编辑治疗

免疫缺陷疾病

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem100

Precise correction of heterozygous SHOX2 mutations in hiPSCs derived from patients with atrial fibrillation via genome editing and sib-selection

基因编辑治疗

心房颤动模型

Patient-specific human induced pluripotent stem cells (hiPSCs) offer unprecedented opportunities for the investigation of multigenic disease, personalized medicine, and stem cell therapy. For heteroge

NIAID Data Ecosystem50

In vivo Ryr2 editing corrects catecholaminergic polymorphic ventricular tachycardia

基因编辑治疗

遗传性心律失常

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal inherited arrhythmia disorder most commonly caused by missense mutations in the RyR2 gene. The goal of this study was to determ

NIAID Data Ecosystem20

Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy

基因编辑治疗

肌营养不良模型

Measurement of base substitution induced by adenine base editor

NIAID Data Ecosystem50

Treatment of a metabolic liver disease by in vivo prime editing in mice

基因编辑治疗

代谢性肝病

Prime editing is a highly versatile CRISPR-based genome editing technology with the potential to correct the vast majority of genetic defects1. However, correction of a disease phenotype in vivo in so

NIAID Data Ecosystem40

Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response

资源简介：

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