Imaging metabolic heterogeneity in breast cancer using hyperpolarized 13C-MRI
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https://www.omicsdi.org/dataset/ega/EGAS00001004118
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Higher 13C-lactate labeling was seen in the more aggressive tumors, including all triple negative breast cancers. There was a significant correlation between lactate labeling and expression of the monocarboxylate transporter (MCT1), which mediates tumor cell pyruvate uptake, and a weaker correlation with expression of LDHA, which catalyzes label exchange between the injected pyruvate and the endogenous lactate pool.EGA study EGAS00001004118
创建时间：
2021-10-04
