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Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX647

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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资源简介:
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX647 Descriptor: 5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-N-[4-(trifluoromethyl)benzyl]pyridin-2-amine, Mast/stem cell growth factor receptor Kit Authors: Zhang, Y, Zhang, C. Deposit date: 2012-11-06 Release date: 2013-03-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor. Proc.Natl.Acad.Sci.USA, 110, 2013
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2012-11-06
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