AIM: Continuous Ca 2+ influx is essential to maintain intracellular Ca 2+ homeostasis and its dysregulation leads to a variety of cellular dysfunctions. In this study, we explored

DataCite Commons2020-08-28 更新70

Transient inositol 1,4,5-trisphosphate-induced Ca2+ release: a model based on regulatory Ca(2+)-binding sites along the permeation pathway.

离子信号转导

离子通道动力学建模

A remarkable property of Ca2+ fluxes through the inositol 1,4,5-trisphosphate (InsP3)-gated Ca2+ channel is that successive increments of InsP3 induce repeated transient release of accumulated Ca2+. T

PubMed Central1994-10-11 更新40

Datasets Manuscript N33D3cpv

离子信号转导

线粒体功能

datasets generated in the manuscript : " High-sensitivity calcium biosensor on the mitochondrial surface reveals that IP3R channels participate in the reticular Ca2+ leak towards mitochondria<

DataCite Commons2023-03-21 更新90

Supplementary Material for: The Mechanism of Injury-Induced Intracellular Calcium Concentration Oscillations in the Endothelium of Excised Rat Aorta

离子信号转导

肝窦内皮细胞损伤

Endothelial injury is the primary event that leads to a variety of severe vascular disorders. Mechanical injury elicits a Ca 2+ response in the endothelium of excised rat aorta, which compri

DataCite Commons2020-09-02 更新50

Independently paced calcium oscillations in progenitor and differentiated cells in an ex vivo epithelial organ

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