NS3/NS4A protease with inhibitor
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4ktc
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资源简介：
NS3/NS4A protease with inhibitor Descriptor: (2R,6S,13aR,14aR,16aS)-6-{[(cyclopentyloxy)carbonyl]amino}-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxooctadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 3,4-dihydroisoquinoline-2(1H)-carboxylate, NS4A peptide, Serine protease NS3, ... Authors: Zhang, H, Ballard, J, Vigers, G.P.A, Brandhuber, B.J. Deposit date: 2013-05-20 Release date: 2013-08-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease. J.Med.Chem., 57, 2014
创建时间：
2013-05-20
