Crystal Structure of BACE with amino thiazine inhibitor LY2886721
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Crystal Structure of BACE with amino thiazine inhibitor LY2886721 Descriptor: Beta-secretase 1, GLYCEROL, N-{3-[(4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide Authors: Timm, D.E. Deposit date: 2014-12-09 Release date: 2014-12-24 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.77 Å) Cite: The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central A beta Pharmacodynamic Responses in Mice, Dogs, and Humans. J.Neurosci., 35, 2015
创建时间：
2014-12-09
