JunB modulates an IRF4-dependent transcriptional program to regulate homeostasis and suppressive functions of effector regulatory T cells. JunB modulates an IRF4-dependent transcriptional program to regulate homeostasis and suppressive functions of effector regulatory T cells

To understand molecular mechanisms by which JunB regulates Treg function, we performed RNA-seq and ChIP-seq analyses of JunB-deficient and control Treg cells (CD4+ CD25hi). This SuperSeries is composed of the SubSeries listed below. Overall design: RNA-seq analysis of WT and JunB-deficient Treg cells. ChIP-seq analysis of JunB,BATF and IRF4 in in vitro-activated Treg cells. Refer to individual Series