Polycomb protein EED in complex with inhibitor: (3R,4S)-1-[(2-bromo-6-fluorophenyl)methyl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine

Protein Data Bank Japan2023-10-04 更新2026-03-21 收录

下载链接：

https://pdbj.org/mine/summary/5u8a

下载链接

链接失效反馈

官方服务：

资源简介：

Polycomb protein EED in complex with inhibitor: (3R,4S)-1-[(2-bromo-6-fluorophenyl)methyl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine Descriptor: (3R,4S)-1-[(2-bromo-6-fluorophenyl)methyl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine, Polycomb protein EED Authors: Jakob, C.G, Zhu, H. Deposit date: 2016-12-14 Release date: 2017-03-15 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.45 Å) Cite: SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding. Bioorg. Med. Chem. Lett., 27, 2017

创建时间：

2016-12-14