The Hippo signaling pathway has become recognized as a context-dependent regulator of cell proliferation, differentiation, and apoptosis in species ranging from Drosophila to human. In this study, we

NIAID Data Ecosystem50

Pancreatic endocrinogenesis multiome

胰腺发育生物学

细胞命运多组学分析

This is a slimmed and processed version of the pancreatic endocrinogenesis (E14.5, 15.5, 16.5) dataset published with "Mapping cells through time and space with moscot", Klein et al., 2024. The raw da

Figshare2024-08-26 更新20

A PDX1 cistrome and single-cell transcriptome resource of the developing pancreas

胰腺发育生物学

单细胞转录组学

Pancreatic and duodenal homeobox 1 (PDX1) is crucial for pancreas organogenesis, yet the dynamic changes in PDX1 binding in human or mouse developing pancreas have not been examined. To address this k

NIAID Data Ecosystem70

A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets

胰腺发育生物学

单细胞转录组学

This scRNA-seq data is an integral part of a manuscript with the above title. Using computational methods, we were able to reconstruct a detailed branched trajectory reflecting pancreatic endocrine di

NIAID Data Ecosystem50

Ribosomal biogenesis genes play an essential and p53-independent role in pancreas development

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