ABO genotyping, expression and methylation analysis of leukemic cell lines.

‘TYPE’ refers to the cell line type and origin, ‘GENO’ refers to the ABO genotype, ‘EXP’ to ABO mRNA expression and ‘METH’ to the ABO promoter CpG island methylation status as determined by MS-SSCA and COBRA (Figure 2). ‘5-AZA’ refers to ABO mRNA expression after the cell line was treated with 5-aza-2′-deoxyxytidine as outlined in the ‘Materials and Methods’. ‘−’ refers to negative ABO expression, ‘+’ refers to positive ABO expression, ‘U’ refers to unmethylated and ‘M’ to methylated ABO promoter region.