DNA damage checkpoint kinases regulate a global network of transcription factors
收藏Alliance of Genome Resources2026-08-01 收录
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DNA damage results in the activation of checkpoint kinases, which phosphorylate downstream effectors that inhibit the cell cycle, activate DNA repair, and cause widespread changes in transcription
DNA损伤可激活检验点激酶（checkpoint kinases），这类激酶会磷酸化下游效应因子，而这些下游效应因子能够抑制细胞周期、激活DNA修复，并引发转录层面的广泛变化。
