Ir(III)-Catalyzed Carbocarbation of Alkynes through Undirected Double C–H Bond Activation of Anisoles
收藏NIAID Data Ecosystem2026-03-10 收录
数据链接：
官方服务：
资源简介：
A novel, electron-deficient cyclopentadienyl iridium(III) catalyst enables sequential cleavage of arene C(sp2)–H and methoxy C(sp3)–H bonds of anisoles, generating reactive metalacycles that insert difluoroalkynes to afford chromenes under mild reaction conditions. This transformation is an arylalkylation of an alkyne–a carbocarbation–via a nonchelate-assisted cleavage of two C–H bonds.
创建时间：
2018-04-11
