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Sodium arsenite induced DNA methylation changes in A549 human epithelial lung carcinoma cells

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NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE44173
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Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 µM, 0.4 µM and 2 µM for 1, 2 and 8 weeks. A549 arsenic dose time response study.
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2014-09-17
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