Sodium arsenite induced DNA methylation changes in A549 human epithelial lung carcinoma cells
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Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 µM, 0.4 µM and 2 µM for 1, 2 and 8 weeks. A549 arsenic dose time response study.
创建时间：
2014-09-17
