Crystal structure of catalytic domain of TNF-alpha converting enzyme (TACE) with inhibitor
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Crystal structure of catalytic domain of TNF-alpha converting enzyme (TACE) with inhibitor Descriptor: (3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE, ADAM 17, ZINC ION Authors: Levin, J.I, Chen, J.M, Laakso, L.M, Du, M, Schmid, J, Xu, W, Cummons, T, Xu, J, Zhang, Y, Jin, G, Cowling, R, Barone, D, Skotnicki, J.S. Deposit date: 2005-06-07 Release date: 2005-09-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates. Bioorg.Med.Chem.Lett., 15, 2005
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2005-06-07
