Crystal structure of dimeric murine SMPDL3A

Crystal structure of dimeric murine SMPDL3A Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... Authors: Zhang, C, Liu, P, Fan, S, Hou, Y. Deposit date: 2023-08-29 Release date: 2023-12-20 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.91 Å) Cite: SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing. Immunity, 56, 2023