CRISPRme Dataset

CRISPRme dataset used to generate data, reports and figures in CRISPRme pubblication (Human genetic diversity alters off-target outcomes of therapeutic gene editing) File_S1_1617_search_results.zip contains top1000 targets for sg1617 guide searched on hg38+1000G+HGDP ngg_spcas9.zip contains complete list of targets for sg1617+13 other ngg guides searched on hg38+1000G+HGDP ngg_spcas9.zip contains complete list of targets for sg1617 guide searched on hg38+1000G+HGDP (no-pam) non_ngg.zip contains complete list of targets for other 6 guides with non-ngg pams searched on hg38+1000G+HGDP inclisiran.zip contains complete list of targets for inclisiran guides searched on hg38+1000G+HGDP (no-pam) nusinersen.zip contains complete list of targets for nusinersen guides searched on hg38+1000G+HGDP (no-pam)