BIOGRID CURATED DATA FOR TUS1 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for TUS1 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Guanine nucleotide exchange factor (GEF) that modulate Rho1p activity; involved in the cell integrity signaling pathway; interacts with Rgl1p; localization of Tus1p to the bed neck is regulated by Rgl1p; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate

TUS1（酿酒酵母S288c）蛋白质-蛋白质、遗传和化学相互作用数据集，由BioGRID（https://thebiogrid.org）编纂；定义：鸟苷酸核苷酸交换因子（GEF），调节Rho1p活性；参与细胞完整性信号通路；与Rgl1p相互作用；Tus1p在床颈部的定位受Rgl1p调控；为tor2突变和多拷贝抑制子，以及ypk1 ypk2双重突变的抑制子；具有潜在Cdc28p底物活性。